DMT1 blocker 1( —— )

Catalog No. M26167 CAS No. 1354790-56-9

DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

DMT1 blocker 1
Note

Research use only, not for human use.
Brief Description

DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo.
Description

DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

CDK2| FLT3| JAK2
Research Area

——
Indication

——

Chemical Information

CAS Number

1354790-56-9
Formula Weight

294.314
Molecular Formula

C16H14N4O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (169.89 mM)
SMILES

Cc1nn(c(O)c1C(=O)Nc1ccccc1)-c1ccccn1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.William AD, et al. Discovery of kinase spectrum selective macrocycle (16E)-14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kina

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